What Should I do if i Get a Headache ?

A headache is a common health condition characterized by pain or discomfort in the head or upper neck area. It is one of the most common reasons people seek medical attention. Headaches can vary in intensity, duration, and frequency and may present with different symptoms depending on the underlying cause.

There are several types of headaches, including:

  1. Tension headaches: These are the most common type of headache and are often described as a dull, aching pain or pressure on both sides of the head. Tension headaches are typically triggered by stress, poor posture, or muscle tension.
  2. Migraine headaches: Migraines are a type of headache characterized by intense throbbing or pulsating pain, often on one side of the head. Migraine attacks are often accompanied by other symptoms such as nausea, vomiting, sensitivity to light and sound, and visual disturbances.
  3. Cluster headaches: Cluster headaches are relatively rare but extremely painful headaches that occur in cyclical patterns or clusters. They often cause severe pain around one eye or on one side of the head and may be accompanied by symptoms such as redness or tearing of the eye, nasal congestion, or restlessness.
  4. Sinus headaches: Sinus headaches are caused by inflammation or infection of the sinus cavities and are often accompanied by symptoms such as facial pain, pressure around the eyes or cheeks, nasal congestion, and postnasal drip.
  5. Rebound headaches: Rebound headaches, also known as medication-overuse headaches, can occur when overuse of pain medications, especially certain types of pain relievers, leads to a cycle of recurring headaches.

Headaches can be caused by a wide range of factors, including stress, tension, muscle strain, poor posture, dehydration, lack of sleep, eye strain, certain foods or food additives, hormonal changes, environmental factors, and underlying health conditions such as sinusitis, migraines, or high blood pressure.

Treatment for headaches depends on the type and underlying cause but may include over-the-counter or prescription pain medications, lifestyle changes, stress management techniques, and addressing any underlying health conditions.

What Should I do if i Get a Headache ?

If you get a headache, there are several steps you can take to alleviate it, depending on the severity and underlying cause of the headache. Here are some general recommendations:

  1. Identify triggers: Try to identify any potential triggers for your headaches, such as stress, dehydration, lack of sleep, certain foods, or environmental factors. Avoiding these triggers may help prevent future headaches.
  2. Rest: If possible, rest in a quiet, dark room. Lie down and close your eyes, as this can help reduce sensory stimulation and ease headache symptoms.
  3. Hydration: Drink plenty of water, as dehydration can sometimes contribute to headaches. However, avoid excessive caffeine or alcohol consumption, as these can sometimes worsen headaches.
  4. Over-the-counter pain relievers: Consider taking over-the-counter pain relievers such as acetaminophen (Tylenol), ibuprofen (Advil, Motrin), or aspirin to help alleviate headache pain. Follow the recommended dosage instructions on the packaging and avoid exceeding the maximum daily dose.
  5. Apply cold or heat: Applying a cold compress or ice pack to the forehead or the back of the neck can help numb the pain and reduce inflammation. Alternatively, some people find relief from applying a warm compress or taking a warm shower.
  6. Practice relaxation techniques: Techniques such as deep breathing, progressive muscle relaxation, meditation, or yoga may help alleviate headache symptoms, especially if stress or tension is a contributing factor.
  7. Massage: Gentle massage of the temples, neck, and shoulders can help relax tense muscles and alleviate headache pain.
  8. Avoid triggers: If you know certain activities, foods, or environmental factors trigger your headaches, try to avoid or minimize exposure to them.

If your headache is severe, persistent, or accompanied by other concerning symptoms such as confusion, difficulty speaking, weakness, numbness, visual disturbances, or a high fever, it’s important to seek medical attention promptly, as these could be signs of a more serious underlying condition.

What is The Max Dosage of Butabital and Why Fiorinal is a Controlled Substance ?

Butalbital (5-allyl-5-isobutylbarbituric acid), is a short to intermediate-acting barbiturate. It has the following structural formula:

butalbital
 

C11H16N2O3          Mol. wt. 224.26
Barbiturates may be habit-forming: Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates.

The average daily dose for the barbiturate addict is usually about 1500 mg. That is 1500mg Butalbital will make you addictive to butalbital.

One tablet fioricet contains 325 mg acetaminophen. FDA attempt to cut down on incidences of potentially fatal liver damage associated with acetaminophen.  The max dosage of acetaminophen is 3000mg per day. But we recommend the max dosage of acetaminophen is 2000mg.  Especially for a patient who drink alcohol.

  • Alcohol consumption substantially increases the risk of acute liver failure from acetaminophen overdose.
  • Liver damage may occur with consumption of only 2,600 mg of acetaminophen in the course of a day in people who have consumed varying amounts of alcohol.

acetaminophen

Acetaminophen effectively lowers fever and relieves minor aches and pains without stomach discomfort and heart issues associated with ibuprofen and other non-steroidal anti-inflammatory drugs (NSAIDs).

It is strongly recommended that people who consume alcohol on a regular basis limit acetaminophen intake to a maximum of 1,000 to 2,000 mg per day. The preference is to stay at the lower end of that range.

If you do not want to hurt yourself, the max dosage of fioricet is six pills per day. We donot suggest a drunk man to take fioricet.

One tablet fioricet contains 50mg butalbital. The average daily dose for the barbiturate addict is usually about 1500 mg (30 Fioricet tablets).  That is five times of acetaminophen max dosage. At this dosage,  you will kill yourself by acetaminophen.

It is very hard to separate butalbital from fioricet or generic fioricet, so fioricet is not controlled substance.

Fiorinal contains a combination of aspirin, butalbital, and caffeine. Aspirin is a pain reliever, as well as an anti-inflammatory and a fever reducer. Butalbital is a barbiturate. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Fiorinal is used to treat tension headaches. This medicine is not for treating headaches that come and go.

It is easy to separate butalbital from Fiorinal, That is why Fiorinal is a controlled substance.

 

 

 

How to Treat Fioricet Overdose

The treatment of Fioricet overdose is complicated by the presence of two substances which are highly toxic when taken in excessive amounts. Fioricet overdoses generally result in toxic amounts of both acetaminophen and butalbital being consumed at once, requiring both overdoses to be treated at once.

Fioricet overdose by anyone and/or any consumption by persons to whom it is not prescribed (particularly children) is always a medical emergency and medical attention must be sought immediately if an overdose or consumption by other persons is suspected.fioricet

Fioricet overdose is often fatal and symptoms may not present for hours following consumption, once initial overdose symptoms present they can progress rapidly and there may not be time to reach appropriate medical care after this point.

Acetaminophen over-exerts its toxicity through the production of a toxic metabolite which produces liver damage in doses of 3,000mg or more per day and acute liver failure in doses above that. The specific antidote to acetaminophen overdose is N-acetyl-cysteine. Kidney failure and stomach bleeding may also occur.

Butalbital overdoses exerts its toxicity through excessive sedation resulting in respiratory depression and ultimately death via hypoxia. Nonlethal overdoses may also result in coma and death. There is no specific antidote to butalbital overdose and treatment is supportive, common treatment regimens generally include the administration of intravenous administration of saline, naloxone, thiamine, glucose, NaHCO3 to alkalize the urine to increase rate of excretion, and activated charcoal via nasogastric tube. It is not uncommon for doctor to recommend observation of the patient in the Emergency Department for a number of hours or admission to the hospital for several days of observation if symptoms are severe and to counsel the patient on drug abuse and/or refer them for psychiatric evaluation.

How to Treat Fioricet Overdosage ?

Treating Fioricet overdosage requires prompt medical attention and intervention to prevent serious complications. Fioricet contains three active ingredients: butalbital, acetaminophen, and caffeine. Overdosing on Fioricet can lead to toxicity from any of these components, with acetaminophen overdose being particularly concerning due to its potential to cause liver damage. Here are some steps for treating Fioricet overdosage:

  1. Seek Emergency Medical Assistance: If you suspect that you or someone else has overdosed on Fioricet, call emergency services immediately or go to the nearest emergency room. Time is critical in cases of overdose, and prompt medical intervention can help prevent serious complications.
  2. Provide Information: Provide healthcare providers with as much information as possible about the amount of Fioricet ingested, the time of ingestion, and any other medications or substances taken concurrently.
  3. Gastric Decontamination: In cases of recent ingestion, healthcare providers may perform gastric decontamination to remove the remaining medication from the stomach. This may involve inducing vomiting or administering activated charcoal to absorb the medication and prevent further absorption into the bloodstream.
  4. Acetaminophen Antidote: If the overdose involves a significant amount of acetaminophen, healthcare providers may administer N-acetylcysteine (NAC), an antidote that helps protect the liver from acetaminophen toxicity. NAC is most effective when administered within 8-10 hours of acetaminophen ingestion but can still provide benefit if given later.
  5. Monitoring and Supportive Care: Patients who have overdosed on Fioricet may require close monitoring of vital signs, liver function tests, and other laboratory parameters. Supportive care may include intravenous fluids, oxygen therapy, and medications to manage symptoms such as nausea, vomiting, and pain.
  6. Treatment of Complications: Depending on the severity of the overdose and associated complications, additional treatments may be necessary. For example, patients with liver damage may require further medical interventions, such as liver transplantation in severe cases.
  7. Psychological Support: Overdosing on medication can be distressing and may indicate underlying mental health issues. Patients who overdose on Fioricet should receive psychological support and counseling to address any underlying issues and prevent future occurrences.

Can You Buy Gabapentin Online?

Yes, you can buy Gabapentin Online! You still need a prescription to buy Gabapentin online, though. Fortunately, you can get a Gabapentin prescription online from a licensed and qualified doctor.

Gabapentin 100mg, Gabapentin 300mg, Gabapentin 400mg, Gabapentin 600mg, Gabapentin 800mg
Gabapentin 100mg, Gabapentin 300mg, Gabapentin 400mg, Gabapentin 600mg, Gabapentin 800mg

What is Gabapentin?

Gabapentin, known sometimes by the generic name Neurontin, is primarily used to diffuse the symptoms of epilepsy.  When used as an analgesic or painkiller, Gabapentin acts through a different mechanism than commonly prescribed pain medicines such as morphine and oxycontin.  Due to this, Gabapentin is thought to be less addictive than opiates – but addiction and abuse may still occur.

PubChem, an NCBI branch, defines “Gabapentin [as] a synthetic analog of the neurotransmitter gamma-aminobutyric acid with anticonvulsant activity. Although its exact mechanism of action is unknown, Gabapentin appears to inhibit excitatory neuron activity. This agent also exhibits analgesic properties. (NCI04)”

Gabapentin Side Effects

Contact your doctor if you experience anything unusual while taking any medication.

Most common Gabapentin side effects:

  • Tiredness
  • Dizziness
  • Headache

Common Gabapentin side effects:

  • Fatigue
  • Double vision
  • Blurred vision
  • Tremors

Less common Gabapentin side effects:

  • Increased appetite
  • Weight gain
  • Arm or leg swelling
  • Back pain
  • Upset stomach
  • Intestinal gas
  • Dry mouth or throat
  • Constipation
  • Dental problems
  • Muscle aches
  • Runny nose
  • Sore throat
  • Speech problems
  • Memory loss
  • Depression
  • Sleep problems
  • Irritability
  • Abnormal thinking
  • Twitching
  • Itching
  • Abrasions
  • Impotence
  • Visual disturbance
  • Anxiety
  • Panic attacks

Rare Gabapentin side effects:

  • Dizziness
  • Depression
  • Suicidal thoughts
  • Seizure
  • Reduced sex drive
  • Broken bones
  • Poor coordination
  • Low red- and white- blood cell counts
  • Flushing
  • Allergic reactions, such as swelling, fever, rash, itching, and trouble breathing

Gabapentin Precautions

You should not take Gabapentin if you are allergic or sensitive to any of its ingredients. It is not recommended to drink alcohol while taking Gabapentin as it may cause more drowsiness than usual. Doctors often recommend abstaining from alcohol completely during the first few days of treatment while figuring out how the drug affects you.

This medication has been associated with seizure development in people without epilepsy. Typically those individuals were taking other medication such as antidepressants, antipsychotics, stimulants, or narcotics.

In the unlikely event that a seizure occurs in an individual who has not experienced a seizure before, a doctor needs to evaluate the individual for an underlying seizure disorder. Contact your doctor immediately (before your next dose) as they likely will need to modify your treatment plan.

Suddenly stopping any antiepileptic drug, including Gabapentin, can increase the chance of seizures, so don’t stop taking it if you are waiting for your doctor to become available.

Special Information on Gabapentin

Gabapentin may make you feel dizzy or tired or interfere with your concentration. Exhibit extreme caution when driving or performing other tasks requiring careful attention.

Alcohol and other depressants are not recommended because it increases dizzy and tired effects.

Contact your doctor if you experience worsening symptoms of depression, suicidal thoughts, panic attacks, anxiety, agitation, restlessness, trouble sleeping, reckless behavior, or any other bothersome or persistent side effects.

Gabapentin Dosage

Adult and child (age 13 and over): 300 – 600 milligrams 3 times a day. Dosage may need to be reduced in individuals with kidney disease.

Child (age 3 – 12) 4.5-7 milligrams per lb. of body weight a day in 3 divided doses to start, increasing gradually for about 3 days to a maximum dosage of 22 milligrams per lb. a day in divided doses.

Child (under the age of 3): not recommended

Gabapentin for Seniors

Seniors may need to take a lower dosage due to decreased kidney function. Make your doctor aware of potential kidney disorders during your evaluation so they can account for that when determining the correct dosage for you.

How To Take Gabapentin

Take Gabapentin exactly as prescribed by your doctor. Do not use prescription doses from someone you know who is taking it.

You can take Gabapentin with or without food. If you experience nausea or stomach discomfort after taking Gabapentin, try eating a small meal before taking your next dose.

Avoid taking Gabapentin along with an antacid, such as Pepto-Bismol or Maalox, as the antacid will interfere with absorption. You can still take antacids, but separate the dose from Gabapentin by at least two hours.

If you forget a dose of Gabapentin, take it as soon as you remember. If it is almost time for your next dose, take the dose you forgot and space the remaining doses evenly throughout the day. Do not take a double dose.

If you are unsure how to take medicine, do not hesitate to contact your healthcare provider or pharmacist. They have received extensive training on answering questions such as a forgotten dose.

Do You Need a Prescription for Gabapentin?

Yes, you need a prescription for Gabapentin. Gabapentin is classified as a controlled substance in:

  • Kentucky
  • Tennessee
  • Virginia
  • West Virginia
  • Michigan

This means you will need to see a doctor in person for a Gabapentin prescription in those states.

If you live elsewhere you will be able to get Gabapentin from an online doctor, like those at our sister site PlushCare.

How Can I Get a Prescription for Gabapentin?

To get a prescription for Gabapentin, a doctor must evaluate you for a disorder. Then the doctor will evaluate potential treatment options and decide whether the risk to benefit ratio of Gabapentin is favorable in your case.

An increasingly popular option for getting prescriptions is going to an online doctor. EverydayDr recommends PlushCare for these types of services. They have same-day access to medical professionals across the country, all of whom have graduated from a top-50 medical institution. You can book an appointment quickly and see a doctor in as little as 15 minutes.

PlushCare is a great platform to get a Gabapentin prescription online. If you live in a state where Gabapentin is not classified as a controlled substance and the doctor decides Gabapentin is an appropriate treatment for you, they will electronically send your prescription to the pharmacy of your choice.

How much does a 30 day supply of Gabapentin cost?

The price of a 30 day supply of Gabapentin varies widely depending on location, dosage, and insurance status. Gabapentin is a widely used drug and is typically covered by insurance.

If you don’t have insurance or your provider does not cover this medication, Gabapentin is available for only $0.19 per 300 milligrams capsule (as of January 2021). An adult taking 300 milligrams three times a day should expect a cost of $17.10 per 30 day supply.

You may be able to save a few dollars by checking the price at multiple local and online pharmacies. Costs of medication are always subject to change.

Gabapentin While Pregnant/Breastfeeding

Gabapentin causes congenital disabilities in laboratory animals. Seizure disorders are known to be associated with increased congenital disabilities in humans. Your doctor will have to weigh the risk of experiencing seizures during pregnancy and the benefit of reducing seizures during pregnancy to decide if taking this medication is right for you.

It is not known if Gabapentin passes into breast milk. Nursing mothers are strongly encouraged to use formula to err on the side of caution.

Pharmacist tips for Fioricet

  • Fioricet can cause excessive sleepiness, dizziness, and lightheadedness. Don’t drive or use any heavy machinery until you know how the medication affects you.
  • Since Fioricet contains some caffeine, be sure to limit how much caffeine you use per day. Too much caffeine can lead to nervousness, shakiness, restlessness, trouble sleeping, and a fast heart rate.
  • Avoid drinking alcohol while taking Fioricet, since it can cause you to be more drowsy and less alert, and raise your risk of accidental injuries and liver damage.
  • Many over-the-counter and prescription medications contain acetaminophen. Don’t take more than 3 to 4 grams of acetaminophen per day to avoid liver damage. Ask your provider what your maximum daily amount of acetaminophen is, since this depends on your provider’s instructions.
  • Use caution if you currently take medications called monoamine oxidase inhibitors (MAOIs), such as phenelzine (Nardil), tranylcypromine (Parnate), or selegiline (Eldepryl). Taking a MAOI with Fioricet can lead to sleepiness, dizziness, and slowed breathing.
  • If you’re using the oral syrup form of Fioricet, use the dosing cup or syringe provided by your pharmacist to measure out your dose. Don’t use kitchen spoons or cups since they might not give you the most accurate dose.
  • Store Fioricet at room temperature in a place out of reach from children due to the life-threatening risk of accidental overdose, misuse, and abuse. If you or someone you know accidentally overdoses on Fioricet, get emergency medical help or call your local poison control center at 1-800-222-1222 right away.

Fioricet Pharmacokinetics

The behavior of the individual components is described below.

Buy Fioricet Online

Butalbital

Butalbital is well absorbed from the gastrointestinal tract and is expected to distribute to most tissues in the body. Barbiturates in general may appear in breast milk and readily cross the placental barrier. They are bound to plasma and tissue proteins to a varying degree and binding increases directly as a function of lipid solubility.

Elimination of butalbital is primarily via the kidney (59% to 88% of the dose) as unchanged drug or metabolites. The plasma half-life is about 35 hours. Urinary excretion products include parent drug (about 3.6% of the dose), 5-isobutyl-5-(2, 3-dihydroxypropyl) barbituric acid (about 24% of the dose), 5-allyl-5(3-hydroxy-2-methyl-1-propyl) barbituric acid (about 4.8% of the dose), products with the barbituric acid ring hydrolyzed with excretion of urea (about 14% of the dose), as well as unidentified materials. Of the material excreted in the urine, 32% is conjugated.

The in vitro plasma protein binding of butalbital is 45% over the concentration range of 0.5-20 mcg/mL. This falls within the range of plasma protein binding (20%-45%) reported with other barbiturates such as phenobarbital, pentobarbital, and secobarbital sodium. The plasma-to-blood concentration ratio was almost unity, indicating that there is no preferential distribution of butalbital into either plasma or blood cells.

Acetaminophen

Acetaminophen is rapidly absorbed from the gastrointestinal tract and is distributed throughout most body tissues. The plasma half-life is 1.25 to 3 hours, but may be increased by liver damage and following overdosage. Elimination of acetaminophen is principally by liver metabolism (conjugation) and subsequent renal excretion of metabolites. Approximately 85% of an oral dose appears in the urine within 24 hours of administration, most as the glucuronide conjugate, with small amounts of other conjugates and unchanged drug.

Caffeine

Like most xanthines, caffeine is rapidly absorbed and distributed in all body tissues and fluids, including the CNS, fetal tissues, and breast milk.

Caffeine is cleared through metabolism and excretion in the urine. The plasma half-life is about 3 hours. Hepatic biotransformation prior to excretion results in about equal amounts of 1-methylxanthine and 1-methyluric acid. Of the 70% of the dose that is recovered in the urine, only 3% is unchanged drug.

Fioricet Ingredient

Fioricet Ingredient
Fioricet Ingredient

Fioricet contains a combination of acetaminophen, butalbital, and caffeine Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Fioricet is used to treat tension headaches that are caused by muscle contractions.

What is Fioricet and Why it can Relieve Headaches ?

Fioricet (Butalbital, Acetaminophen, and Caffeine Tablets, USP) is supplied in tablet form for oral administration.

Each tablet contains the following active ingredients:
butalbital USP . . . . . . . . . .50 mg
acetaminophen USP . . . . 325 mg
caffeine USP . . . . . . . . . . .40 mg

Fioricet contains Butalbital, Acetaminophen, and Caffeine. Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Butalbital

Butalbital is well absorbed from the gastrointestinal tract and is expected to distribute to most tissues in the body. Barbiturates in general may appear in breast milk and readily cross the placental barrier. They are bound to plasma and tissue proteins to a varying degree and binding increases directly as a function of lipid solubility.

Elimination of butalbital is primarily via the kidney (59% to 88% of the dose) as unchanged drug or metabolites. The plasma half-life is about 35 hours. Urinary excretion products include parent drug (about 3.6% of the dose), 5-isobutyl-5-(2, 3-dihydroxypropyl) barbituric acid (about 24% of the dose), 5-allyl-5(3-hydroxy-2-methyl-1-propyl) barbituric acid (about 4.8% of the dose), products with the barbituric acid ring hydrolyzed with excretion of urea (about 14% of the dose), as well as unidentified materials. Of the material excreted in the urine, 32% is conjugated.

The in vitro plasma protein binding of butalbital is 45% over the concentration range of 0.5-20 mcg/mL. This falls within the range of plasma protein binding (20%-45%) reported with other barbiturates such as phenobarbital, pentobarbital, and secobarbital sodium. The plasma-to-blood concentration ratio was almost unity, indicating that there is no preferential distribution of butalbital into either plasma or blood cells.

Acetaminophen

Acetaminophen is rapidly absorbed from the gastrointestinal tract and is distributed throughout most body tissues. The plasma half-life is 1.25 to 3 hours, but may be increased by liver damage and following overdosage. Elimination of acetaminophen is principally by liver metabolism (conjugation) and subsequent renal excretion of metabolites. Approximately 85% of an oral dose appears in the urine within 24 hours of administration, most as the glucuronide conjugate, with small amounts of other conjugates and unchanged drug.

Caffeine

Like most xanthines, caffeine is rapidly absorbed and distributed in all body tissues and fluids, including the CNS, fetal tissues, and breast milk.

Caffeine is cleared through metabolism and excretion in the urine. The plasma half-life is about 3 hours. Hepatic biotransformation prior to excretion results in about equal amounts of 1-methylxanthine and 1-methyluric acid. Of the 70% of the dose that is recovered in the urine, only 3% is unchanged drug.

Fioricet Mechanism of Action

Fioricet is a brand name consisting of a combination of butalbital (a barbiturate), APAP and caffeine which is indicated for the treatment of tension headaches, muscle contraction headaches and post-dural puncture headaches. Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Each tablet contains the following active ingredients:

      • butalbital USP . . . . . . . . . .50 mg
      • acetaminophen USP . . . . 325 mg
      • caffeine USP . . . . . . . . . . .40 mg

Butalbital (5-allyl-5-isobutylbarbituric acid), is a short to intermediate-acting barbiturate. Butalbital belongs to the group of medicines called barbiturates.

Barbiturates act in the central nervous system (CNS) to produce their effects. When butalbital is used for a long time, it may become habit-forming, causing mental or physical dependence.

However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain.

Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. It has the following structural formula:

Acetaminophen (4´-hydroxyacetanilide), is a non-opiate, non-salicylate analgesic and antipyretic. Acetaminophen is used to relieve pain and reduce fever in patients.

It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.

It has the following structural formula:Caffeine (1,3,7-trimethylxanthine), is a central nervous system stimulant.Caffeine is a CNS stimulant that is used with pain relievers to increase their effect. It has also been used for migraine headaches.

However, caffeine can also cause physical dependence when it is used for a long time. This may lead to withdrawal (rebound) headaches when you stop taking it.

What you Should Know When you Buy Fioricet Online

Buying fioricet without a a local doctor’s prescription is possible here in fioricetbargain.com. With fioricetbargain.com, you can buy cod fioricet online, you can even buy card fioricet, visa fioricet, Mastercard fioricet online. Our card fioricet pharmacy is only for returned COD customers and we will tell you how to buy fioricet online using credit card if you have successfully accepted a COD fioricet or COD Gabapentin order.

For COD fioricet orders, We only accept Money Orders of USPS for COD payment. We do not accept any personnel Check or small company money order.

If you have paid us bounced check or fraud check once, we will place you into customer blacklist, almost all online pharms share the same blacklist. You will not be possible to order prescription online any more.  You also should know your own health condition before you buy fioricet online.

Your first Fioricet or Gabapentin prescription must be approved by your local doctor. Our online doctors can approve your prescription too but our doctors’ decisions are based on your health conditions your provided to us. You must complete the health conditions very honestly. Some patients are not allowed to buy fioricet online in our network.

    1. You have porphyria;
    2. You have recently used alcohol;
    3. You have recently used sedatives, tranquilizers, or other narcotic medications;
    4. You have taken a MAO inhibitor in the past 14 days because A dangerous drug interaction could occur;
    5. You have liver , heart disease, kidney disease;
    6. You have  a history of alcoholism or drug addiction;
    7. You have asthma, sleep apnea, or other breathing disorder;
    8. You have stomach ulcer or bleeding;
    9. You have a history of skin rash caused by any medication;
    10. You have a history of mental illness or suicidal thoughts;
    11.  You use medicine to prevent blood clots;
    12. You are pregnant because your baby could become dependent on the drug;
    13. You are now breast feeding because Fioricet can pass into breast milk and may harm a nursing baby.

When you are not allowed to buy fioricet online does not mean you can not take fioricet, you must go to your local doctors and local pharmacies to get your prescription. You need your doctors and pharmacists to check you face to face.

Fioricet Overdose Signs, Symptoms and Treatment

Fioricet Signs and Symptoms

Toxicity from barbiturate poisoning include drowsiness, confusion, and coma; respiratory depression; hypotension; and hypovolemic shock.

In acetaminophen overdosage: dose-dependent, potentially fatal hepatic necrosis is the most serious adverse effect. Renal tubular necroses, hypoglycemic coma, and thrombocytopenia may also occur. Early symptoms following a potentially hepatotoxic overdose may include: nausea, vomiting, diaphoresis, and general malaise. Clinical and laboratory evidence of hepatic toxicity may not be apparent until 48 to 72 hours post-ingestion. In adults hepatic toxicity has rarely been reported with acute overdoses of less than 10 grams, or fatalities with less than 15 grams.

Acute caffeine poisoning may cause insomnia, restlessness, tremor, and delirium, tachycardia and extrasystoles.

Fioricet overdose Treatment

A single or multiple overdose with this combination product is a potentially lethal polydrug overdose, and consultation with a regional poison control center is recommended.

Immediate treatment includes support of cardiorespiratory function and measures to reduce drug absorption. Vomiting should be induced mechanically, or with syrup of ipecac, if the patient is alert (adequate pharyngeal and laryngeal reflexes). Oral activated charcoal (1 g/kg) should follow gastric emptying. The first dose should be accompanied by an appropriate cathartic. If repeated doses are used, the cathartic might be included with alternate doses as required. Hypotension is usually hypovolemic and should respond to fluids. Pressors should be avoided. A cuffed endotracheal tube should be inserted before gastric lavage of the unconscious patient and when necessary, to provide assisted respiration. If renal function is normal, forced diuresis may aid in the elimination of the barbiturate. Alkalinization of the urine increases renal excretion of some barbiturates, especially phenobarbital.

Meticulous attention should be given to maintaining adequate pulmonary ventilation. In severe cases of intoxication, peritoneal dialysis, or preferably hemodialysis may be considered. If hypoprothrombinemia occurs due to acetaminophen overdose, vitamin K should be administered intravenously.

If the dose of acetaminophen may have exceeded 140 mg/kg, acetylcysteine should be administered as early as possible. Serum acetaminophen levels should be obtained, since levels four or more hours following ingestion help predict acetaminophen toxicity. Do not await acetaminophen assay results before initiating treatment. Hepatic enzymes should be obtained initially, and repeated at 24-hour intervals.

Methemoglobinemia over 30% should be treated with methylene blue by slow intravenous administration.

Toxic Doses (for adults)

 

Butalbital: toxic dose 1 g (20 tablets)
Acetaminophen: toxic dose 10 g (30 tablets)
Caffeine: toxic dose 1 g (25 tablets)

In all cases of suspected overdosage, call your Regional Poison Control Center to obtain the most up-to-date information about the treatment of overdosage. Telephone numbers of certified Regional Poison Control Centers are listed in the Physicians’ Desk Reference®*.